He is reported to have died at the Korle Bu Teaching Hospital Saturday night.
Rev. Asante Antwi who is a member of the Council of Elders of the ruling New Patriotic Party was known for his criticisms against the NDC when the party was in power.
Rev. Asante-Antwi became President of the Methodist church in August 1997.
He was chair of the disciplinary committee of the NPP that suspended then party chairman Paul Afoko.